The Basilica of St John Lateran — in Italian, the Basilica di San Giovanni in Laterano — is the cathedral church of Rome and the official ecclesiastical seat of the Pope. Officially named Archibasilica Sanctissimi Salvatoris (Archbasilica of the Most Holy Savior), it is the oldest and ranks first (being the only cathedral in Rome) among the four major basilicas of Rome, and holds the title of ecumenical mother church (mother church of the whole inhabited world) among Catholics. The current archpriest of St. John Lateran is Camillo Ruini, Cardinal Vicar General for the Diocese of Rome. An inscription on the façade, Christo Salvatore, dedicates the Lateran as Archbasilica of the Most Holy Saviour, for the cathedrals of all patriarchs are dedicated to Christ himself. As the cathedral of the Bishop of Rome, containing the papal throne (Cathedra Romana), it ranks above all other churches in the Catholic Church, even above St. Peter's Basilica in the Vatican.The site on which the Basilica sits was occupied during the early Roman Empire by the palace of the gens Laterani. The Laterani served as administrators for several emperors; Sextius Lateranus was the first plebeian to attain the rank of consul. One of the Laterani, Consul-designate Plautius Lateranus, became famous for being accused by Nero of conspiracy against the emperor. The accusation resulted in the confiscation and redistribution of his properties. The square in front of the Lateran Palace has an obelisk built by Pharaoh Tuthmosis III in Karnak, and placed in the Circus Maximus before being re-erected in its current place. The Lateran Palace fell into the hands of the emperor when Constantine I married his second wife Fausta, sister of Maxentius. Known by that time as the "Domus Faustae" or "House of Fausta," the Lateran Palace was eventually given to the Bishop of Rome by Constantine. The actual date of the gift is unknown but scholars believe it had to have been during the pontificate of Pope Miltiades, in time to host a synod of bishops in 313 that was convened to challenge the Donatist schism, declaring Donatism as heresy. The palace basilica was converted and extended, eventually becoming the cathedral of Rome, the seat of the popes as patriarchs of Rome. The official dedication of the Basilica and the adjacent Lateran Palace was presided over by Pope Sylvester I in 324, declaring both to be Domus Dei or "House of God." In its interior, the Papal Throne was placed, making it the Cathedral of the Bishop of Rome. In reflection of the basilica's primacy in the world as mother church, the words Sacrosancta Lateranensis ecclesia omnium urbis et orbis ecclesiarum mater et caput are incised in the main door, meaning "Most Holy Lateran Church, of all the churches in the city and the world, the mother and head." The Lateran Palace and basilica have been rededicated twice. Pope Sergius III dedicated them to Saint John the Baptist in the 10th century in honor of the newly consecrated baptistry of the Basilica. Pope Lucius II dedicated the Lateran Palace and basilica to Saint John the Evangelist in the 12th century. However, St. John Baptist and St. John the Evangelist are regarded as co-patrons of the Cathedral, the chief patron being Christ the Saviour himself, as the inscription in the entrance of the Basilica indicates, and as is tradition in the Patriachal Cathedrals. Thus, the Basilica remains dedicated to the Saviour. That is why sometimes the Basilica will be referred to by the full title of Archbasilica of the Most Holy Saviour and of Sts. John Baptist and John Evangelist in the Lateran. The church became the most important shrine in honor of the two saints, not often jointly venerated (but see Peruzzi Chapel, Santa Croce, Florence). In later years, a Benedictine monastery was established at the Lateran Palace, devoted to serving the basilica as a devotional to the two saints. Every pope from Miltiades occupied the Lateran Palace until the reign of the French Pope Clement V, who in 1309 decided to transfer the official seat of the Catholic Church to Avignon, a papal fief that was an enclave within France. During the Avignon papacy, the Lateran Palace and the basilica began to decline. Two destructive fires rampaged through the Lateran Palace and the basilica, in 1307 and again in 1361. In both cases, the Avignon papacy sent money to their bishops in Rome to cover the costs of reconstruction and maintenance. Despite the action, the Lateran Palace and the basilica lost their former splendor. When the Avignon papacy formally ended and the Bishop of Rome again resided in Rome, the Lateran Palace and the basilica were deemed inadequate considering the accumulated damage. The popes took up residency at the Basilica di Santa Maria in Trastevere and later at the Basilica di Santa Maria Maggiore. Eventually, the Palace of the Vatican was constructed, and the papacy moved in; the papacy remains there today.